Rafael Nadal has withdrawn from the season-ending ATP Finals due to a persistent abdominal injury and will take the time off to have ankle surgery.
The Spaniard lost his place as world number one last week when injury forced him to pull out of the Paris Masters, with Novak Djokovic moving to the top of the rankings.
And Nadal will not get the opportunity to end the year on a high as he will not play in London, citing both last week's abdominal issue and a long-standing ankle problem for his absence.
"It has been a complicated year - very good at the tennis level when I have been able to play and, at the same time, very bad as far as injuries are concerned," Nadal wrote on Twitter.
"I have done everything possible to get to the end of the season in good condition, both to Paris and to London, doing things well, and I really wanted to play.
"Unfortunately, I had the abdominal problem in Paris last week and I also have a free body in the ankle joint that has to be removed in the operating room [on Monday].
"We had detected it for some time and it occasionally bothered me. However, since the problem in the abdominal muscle also prevents me from playing in London, we are taking the time to remove the free body and avoid future problems.
"This way I hope to be in full condition for next season."
Nadal has not featured on the ATP World Tour since retiring in the semi-finals of the US Open in September, also suffering this year with hip and knee problems.
The 32-year-old won the French Open - his 17th grand slam title - but he competed in just three hard-court tournaments in 2018, winning the Rogers Cup while retiring at both the Australian Open and at Flushing Meadows.
Djokovic is set to end the year as number one, having enjoyed a sensational run of results that saw him triumph at Wimbledon and the US Open.
14. November 2018
|Messi will make Argentina return, says Maradona|
|Warriors drop Hawks as Green serves suspension|
|In-form Healy sends Australia into semis|
|Former NBA star McGrady says Carmelo Anthony should retire|
|Celtics´ Smart: We have to look at ourselves in the mirror|
|Federer plays down preferential treatment talk|
|Mourinho is better than Guardiola – Maradona|
|Mbappe plays down Pele comparisons|
|Don´t worry bro – Mendy responds to Trump|
|Melvin, Snitker win manager of the year awards|
|Warriors´ Green suspended for Hawks clash|
|Asensio: It´s not for me to lead Madrid|
|Rooney ready to enjoy England farewell after pressure of ´Golden Generation´|
13. November 2018
|Ludwigsburg stun high-flying Murcia in BCL|
|Rams v Chiefs moved to LA due to Mexico City field conditions|
|Skriniar discussing new Inter contract, confirms agent|
|Former Barcelona boss Martino named MLS Coach of the Year|
|Bell fails to report to Steelers, will sit out rest of season|
|Federer back on track after dismal Thiem display|
|Udinese appoint Nicola after sacking Velazquez|
|Monaco deny they broke rules regarding youth recruitment|
|Del Bosque, Zidane, Lopetegui - The former Castilla coaches Solari follows into Real Madrid hot seat|
|Ozil rejected ´crazy offers´ from Asia, reveals agent|
|Real Madrid appoint Solari on permanent basis|
|LeVert avoids need for surgery, should return this season|
|Neuer confident despite concerns over Bayern Munich form|
|All I ever wanted to do is win, says Sixers signing Butler|
|Pogba: Coming home to United was the best feeling ever|
|Watson among four signing new Bath deals|
|Susanna Dinnage to replace Scudamore as Premier League chief executive|
|Murray commits to Brighton until 2020|
|Rooney rejected chance of pre-World Cup farewell|
|Impressive Anderson thrashes Nishikori|
|Ozil´s Germany absence a ´pity´, says Sane|
|Rooney: I´ll finish my career in the US|
|McIlroy unsure of 2019 European Tour membership|
|Australian Open dismisses concerns of Federer scheduling bias|
|Hue Jackson joins Bengals staff as ´special assistant´|
|Real Madrid confirm Reguilon injury|
|Higuain handed two-match ban for Juve meltdown|
|Kruis ruled out for England as Jones calls up uncapped quartet|
|A year on from Italy failure, Ventura leaves Chievo after four games|
|Bairstow misses out as unchanged England promote Stokes|
|Recalled Alba denies Luis Enrique bust-up|
|´Unhappy´ Christensen won´t push for Chelsea exit|
|Nadal to make Abu Dhabi comeback in December|
|Taijul helps Bangladesh tighten their grip despite Taylor ton|
|Neymar joining Real Madrid wouldn´t hurt Iniesta|
|It´s just team spirit - Livingston not worried by Durant-Green exchange|
|Trippier out of England squad with groin injury|
|Ex-Sri Lanka international Lokuhettige charged by ICC|
|Former England and Chelsea star Joe Cole retires|
|Nets offer support to LeVert following serious leg injury|
|Panenka proud Sergio Ramos imitates his penalties|
|Liverpool´s Alisson seeks patience to reach potential|
|Anthony Davis leads Pelicans, Clippers hold off Warriors in OT|
|Lindelof rues international break for Man Utd|
|Shaqiri confident in more goals for Liverpool|
|Giants too good for 49ers in crunch time|
|Southgate named honorary Yorkshireman|
|Nicky Butt: Manchester United are low on confidence|
|Criticism of Barcelona star Dembele is overblown - agent|
|Thibodeau discusses Butler trade: We thought this was the best deal for us|
|Acuna, Ohtani win rookie of the year awards|
|LeBron James on Lakers’ early season struggles: ‘I almost cracked’|
|Welbeck has successful second operation on broken ankle|
|UEFA warns FFP cases can be reopened based on ´new information´|
12. November 2018
|Foakes to keep England place for second Test|
|WATCH: Rooney looking sharp in England training return|
|Mbappe: Money in football is truly indecent|