Sergio Aguero will not play again for Manchester City this season and will now focus upon recovering in time for Argentina's World Cup campaign, his club manager Pep Guardiola has confirmed.
Aguero underwent keyhole surgery on his right knee in Barcelona earlier this week after he failed to fully recover from a heavy challenge by Ashley Young in City's 3-2 derby defeat against Manchester United.
United's shock 1-0 loss to West Brom last weekend meant City wrapped up the Premier League title with five matches to spare and Aguero, who was named in the PFA Team of the Year, will not feature again at the Etihad Stadium until 2018-19.
Asked whether the 29-year-old's season was over, Guardiola told a news conference: "Here, yeah. It is four or five weeks. Hopefully we are going to try for him to be ready for the World Cup.
"He is in Barcelona right now for the first part of the rehabilitation."
Muy feliz y orgulloso por integrar el Equipo del Año de la Premier League de la PFA Gracias #PFAawards! Y felicitaciones a mis compañeros!//I'm very happy and proud to be part of The PFA Premier League Team of the Year Thanks #PFAawards! Congratulations to my teammates! https://t.co/EMkYqUPjTa— Sergio Kun Aguero (@aguerosergiokun) April 18, 2018
Aguero's attention is now firmly fixed upon Argentina's World Cup opener against Iceland in Moscow on June 16.
Jorge Sampaoli has ample striking options at his disposal – Gonzalo Higuain and Paulo Dybala were left out of his squad for last month's friendlies against Italy and Spain – but City's all-time leading scorer had looked set to be a key part of their tilt for World Cup glory in an attack led by Lionel Messi.
However, Argentina's team doctor Homero D'Agostino said this week that he fears Aguero will struggle to be at peak fitness by the time Russia 2018 comes around.
"That a player has undergone an arthroscopy with 60 days to go before the World Cup is worrying," D'Agostino told Radio 10.
"The recovery process will require at least five weeks. When one has old injuries, the recovery process is not as fast as one would like it to be. It's never going to be less than three or four weeks, or even more.
"I imagine that he will not arrive 100 per cent fit with the limited time that is left before the World Cup. The anatomy is the anatomy. The injury is what it is. He can try but I don't think he will arrive 100 per cent.
"The important thing is to know what he had. The doctors would have tried to resolve the issue in a conservative manner, non-surgically, but they were unsuccessful. The arthroscopy is a process that you do when there are old injuries."
23. Mai 2018
|Bellamy confirms talks with Brisbane Broncos|
|Ref took Champions League final away from Roma - Under|
|Goals galore and sinking City - Liverpool´s road to the Champions League final|
|Benitez: Winning Champions League changed my life|
|Brewers extend Diamondbacks´ losing streak to six|
|Weidenfeller bids farewell in Schmelzer´s last game as Dortmund captain|
|Owen surprised by Zidane success|
|Rockets break Warriors´ 16-game home postseason win streak|
|Bennett keen to see out contract as Broncos target Bellamy|
|Copa Libertadores Review: Silva helps Cruzeiro into last 16|
|Chargers tight end Henry suffers torn ACL|
|WATCH: Harden dunks all over Green|
|Madrid are linked to 50 players – Ronaldo laughs off Neymar rumours|
|Giants sign wide receiver Shepard|
|Salah wouldn´t improve Real Madrid – Del Bosque|
|Stevens says Tatum should´ve been unanimous All-Rookie First Team selection|
|Rodgers on Bryant: If he ends up here, we´ll welcome him|
|Jets´ Hackenberg dealt to Raiders for 2019 conditional pick|
|Mets sign Bautista, start him same day|
|Warriors´ Iguodala ruled out for game four|
|Guzman called up as Romero replacement for Argentina|
|Gaya signs new five-year Valencia contract|
|Celta appoint Antonio Mohamed as new coach|
|Klopp: Real Madrid have no weaknesses|
|Strauss ´stepping away´ from England role to support wife|
|Argentina rule Romero out of World Cup|
|Emery´s website appears to confirm Arsenal appointment|
22. Mai 2018
|´Inspiring´ Guardiola has made Fleetwood a better golfer|
|Two trophies in a week! Torres leaves Atletico Madrid in style|
|I died a thousand deaths - Yates set for Giro defensive after time trial|
|Hamsik hints at Napoli exit amid China rumours|
|Rowett swaps Derby for Stoke|
|Thiem comfortable in victory as rain delays Wawrinka|
|Schmelzer gives up Borussia Dortmund captaincy|
|Top seed Stephens struggling at Nuremberg Cup|
|This is the wrong information - Vieira rejects Nice speculation|
|France rest Guirado, recall Thomas for New Zealand tour|
|Warriors´ Iguodala upgraded to questionable for game four|
|Simmons, Mitchell unanimous picks for NBA All-Rookie first team|
|AC Milan referred over alleged FFP breaches|
|F1 Raceweek: Ferrari and Red Bull target Monaco upturn|
|Horoya 2 Mamelodi Sundowns 2: Camara header denies visitors´ comeback|
|Du Plessis rescue mission takes Super Kings to IPL final|
|Seedorf to leave relegated Deportivo|
|Wenger turned down Real Madrid ´two or three times´|
|Kane dreams of lifting World Cup trophy as England captain|
|UEFA opens disciplinary proceedings against Liverpool & Roma|
|Yates stays on course for Giro title, Dennis wins time trial|
|Brighton sign Nigeria international Balogun|
|Ronaldo again pips LeBron and Messi as sport´s most famous star|
|Marcelo fears backlash if Madrid lose Champions League final|
|Messi joins Argentina´s World Cup training camp|
|FIFA finds no doping cases in Russia´s World Cup squad|
|Liverpool´s strikeforce reminds Ronaldo of Real Madrid|
|Hysaj staying at Napoli ´regardless of Sarri´s future´|
|Amir fully fit for Lord´s Test|
|A fast start to life - The Golden Knights and the expansion teams who excelled early|
|Molina gets two-year anti-doping ban for positive test after Joshua bout|
|Ramos: We´re a vintage Real Madrid team|
|Klopp key to controlling Liverpool emotions, says Alonso|
|Bjorn names Westwood, Harrington, Donald and McDowell as Europe vice-captains|
|Scarlets players left wounded by ´shocking´ Scotstoun pitch|
|Arsenal fined £20,000 for Leicester penalty protest|
|Storm offer Bellamy ´significant´ deal amid reported Broncos interest|
|Rashford writes moving tribute on anniversary of Manchester Arena attack|
|Heaton backs Kane´s captaincy credentials|
|Salah deserves Ballon d´Or if Liverpool win Champions League – Owen|
|Wasps flanker Willis out for up to a year|
|Real Madrid v Liverpool: Is the Champions League enough to save Zidane?|
|I was left out on reputation - Nainggolan angered by World Cup snub|