Jack Nowell is a major doubt for England's November internationals after he suffered a fractured cheekbone and eye socket playing for Exeter Chiefs on Saturday.
The winger sustained a blow to the left-side of his face during the Chiefs' victory over Newcastle Falcons in the Premiership and early reports have suggested he will miss all of England's matches next month.
Eddie Jones' side host Argentina, Australia and Samoa at Twickenham in November and are already without Billy Vunipola, Manu Tuilagi and Jack Clifford.
Nowell – who has scored 11 tries in 23 appearances for England – could join that list, according to Rob Baxter, but that will depend on whether the 24-year-old requires surgery to fix the problem.
"Jack has got a couple of fractures in the top of his check and eye socket," Baxter, Exeter's director of rugby, said on Wednesday.
"At this stage, it is looking likely he will require an operation to settle it down. Until the surgeon moves in and does some more investigation, that's about as far as I can tell you.
"Depending on when the operation happens, if it is definitely required, which is looking likely, and the severity of the injury, that will then decide whether there is no way back for the autumn internationals.
"It is still a little early to write him off for the whole of the autumn internationals, but that is something we will assess in the next week or so."
Baxter added: "I am disappointed for him personally. He is in good form, starting this season really well for us, and obviously he wanted to have a couple of big rounds in the European Champions Cup to get himself right in the frame for England.
"That, unfortunately, has been damaged now with a pretty innocuous and unfortunate injury. Now, he is going to be held back for the next six to eight weeks.
"It is in and around his eye. We are not anticipating any issues with his vision but obviously there are optical nerves and facial nerves around that area that an operation will disturb. Those things will take a little while to settle as well.
"I don't want to say the wrong thing. Until we have fully got right into the crux of what is going on there…we are still waiting to see the consultant.
"I think six weeks from the time of injury is a figure that we've had bandied around. There is the potential for it to be four weeks, there is the potential for it to be eight weeks."
20. September 2018
|Ryder Cup pick Garcia shoots 66 at Portugal Masters|
|Ronaldo, Zidane, Cantona and the most infamous red cards|
|Villarreal 2 Rangers 2: Arfield and Lafferty steal point for Gerrard´s men|
|PAOK 0 Chelsea 1: Willian strikes as Morata misfires|
|Rain delays Ostapenko in Seoul, Wang books Guangzhou semi|
|Pochettino backs Kane to end goal drought|
|We figured it out - 76ers´ Markelle Fultz rebuilds jump shot|
|Joshua: Povetkin my second-toughest fight|
|Relaxed Pochettino not pushing panic button|
|Why Manchester City fans must fix their relationship with the Champions League|
|Majestic Giorgi ends Wozniacki´s reign in Tokyo|
|Pochettino unwilling to risk Alli fitness|
|Bigger Champions League tests to come, warns Pogba|
|Eight for 10! - Nadeem spins his way to world-record figures|
|A 4-1 lead cut to 3-2 by VAR, but Quakes have no complaints after Atlanta defeat|
|UEFA opens disciplinary proceedings against Ronaldo|
|Joshua v Povetkin: Recapping AJ´s previous world title defences|
|Players told to ink twice over showing tattoos at Rugby World Cup in Japan|
|Mariano targeting Spain call-up after goalscoring Madrid return|
|Pandya, Axar and Thakur out of Asia Cup|
|England omit Cipriani, Tuilagi and Ashton called up|
|Can reacts to Ronaldo´s red card: We are not women|
|One Year to Go: Five Rugby World Cup debutants set to shine|
|Shy Osaka not comfortable with new-found fame|
|Belgium and World Cup winners France make FIFA rankings history|
|Ronaldo wanted to impress - Bernardeschi sympathises after Juve superstar´s red|
|Van Dijk warns Liverpool: Believe we can win trophies or stay home|
|Menezes complains of anti-Brazilian conspiracy after Dede´s VAR red|
|Diamondbacks rout Cubs to remain in postseason picture|
|Modric embraces Ballon d´Or chants as Di Francesco backs Madrid star for award|
|MLS Review: Martinez helps Atlanta stage comeback amid VAR controversy|
|Kerevi recommits to Wallabies, Reds|
|Lyon to ban fan for life after footage of Nazi salute emerges|
|Milan must respect opponents – Gattuso not underestimating Dudelange|
|Copa Libertadores Review: Zarate leads Boca, River draw|
|Mourinho: Dalot can play at Man United for more than 10 years|
|Johnson hoping to erase East Lake demons|
|´No question´ Fitzgerald faces Bears, says Cardinals´ Wilks|
|Rodgers says roughing the passer penalties are ´going the wrong direction´|
|Ravens fined $200,000 for violating communication policy|
|LeBron James set to star in ´Space Jam´ sequel|
|Ronaldo red card ´absurd´, says Pjanic|
|Kovac hails ´special´ Sanches after Bayern goal|
|Marcelino: Tearful Ronaldo said he did nothing wrong|
|Fernandinho takes blame for Man City´s Lyon loss|
|Lovren denies any wrongdoing after perjury charge|
|Plzen boss Vrba slams late mistakes|
|I almost scored as many as Messi - Tagliafico the unlikely hero for Ajax|
|Ronaldo deserves Ballon d´Or not Modric, says Casemiro|
|United fan Rafael - I´ve never lost at City|
|Davis explains abrupt mid-game NFL retirement: ´Football is not for me´|
|Lopes pays tribute to under-fire Lyon coach Genesio|
|Toulon´s Bastareaud handed five-week ban|
|Steelers WR Brown disciplined for missing meeting|
|Arteta refuses to make excuses for Manchester City´s Lyon loss|
|Allegri calls for VAR after Ronaldo´s contentious red card|
|Championship Review: Boro go second, Birmingham still winless|
|Lopetegui: Mariano took his chance|
|Juventus proved their quality after Ronaldo red card - Bonucci|
|Pogba ´class´ impresses Mourinho|
19. September 2018
|Man City not Champions League favourites, insists Bernardo Silva|
|Isco calls for Modric to win Ballon d´Or after Champions League win|
|Wawrinka into last eight in St Petersburg|
|Goal hero Pogba is one of the best in the world - Shaw|
|Sane SOS can´t salvage sorry City display|
|Hoffenheim will learn lessons from Shakhtar draw, insists Nagelsmann|
|Valencia 0 Juventus 2: Pjanic hits the spot after Ronaldo sees red|
|Viktoria Plzen 2 CSKA Moscow 2: Krmencik heroics undone by late show|
|Benfica 0 Bayern Munich 2: Sanches returns to haunt his former club|
|Young Boys 0 Manchester United 3: Pogba double inspires Red Devils|