The quarter-final line-up for the Champions League will be completed this week, with Tuesday's ties both finely balanced.
Manchester United had David de Gea to thank for a battling 0-0 draw in Sevilla, but will be hoping to spend more time on the front foot at Old Trafford.
Roma have the benefit of an away goal from the first leg against Shakhtar Donetsk, but will need to score at least once to progress after losing 2-1.
Here we look at some of the best Opta numbers ahead of the two matches.
Roma v Shakhtar Donetsk
4 - Shakhtar Donetsk have won four of their five competitive games against Roma (L1), all in the Champions League.
52 - More than half of the teams who lose the first leg of a Champions League knockout game away from home 2-1 end up progressing (52 per cent - 12/23).
4 - However, Roma have been eliminated from all four Champions League knockout ties in which they have lost the first leg (home or away).
1 - The Ukrainian side are aiming to reach the Champions League quarter-finals for the first time since the 2010-11 campaign – which they did so by beating Roma 6-2 on aggregate in the round of 16.
3 -The Italian side have kept a clean sheet in each of their last three Champions League home games, winning the last two (D1).
Manchester United v Sevilla
1 - Manchester United have only lost one of their last nine home Champions League games against Spanish sides (W5 D3), that came against Real Madrid at this stage in 2012-13.
70 - Of the away sides who have drawn the first leg of a Champions League knockout tie 0-0, 70 per cent end up progressing to the next round (21/30).
15 - Manchester United haven't managed to score more than one goal in any of their last 15 Champions League encounters with Spanish opposition (seven goals in total).
0 - Sevilla have never won a Champions League game in England (D1 L3), with that one draw coming at Liverpool in this season's group stages.
1 - Starting with the 2011 final, Manchester United have only won one of their last eight Champions League knockout games (D3 L4).
7 - Jose Mourinho has only lost seven of his previous 69 Champions League home games as manager (W48 D14), though five of those defeats have been against Spanish opposition.
12. Dezember 2018
|Butler opens up about heated Timberwolves practice|
|Spurs achieved ´mission impossible´, says Pochettino|
|Dembele stunner pleases Barca boss Valverde|
|Van Dijk lauds ´fantastic´ Alisson|
|Van Dijk´s tackle on Mertens worthy of red card – Ancelotti|
|Klopp ´would have paid double´ for Alisson|
|Klopp: I don´t care about Madrid revenge mission|
|Tension and anxiety got to Inter, laments Spalletti|
|Tuchel hails magnificent PSG as Red Star win seals last-16 spot|
|Mbappe admits frank discussions inspired PSG´s Champions League progress|
|Klopp: Napoli had no answers to outstanding Liverpool|
|Pochettino proud of ´massive, massive achievement´ for Spurs|
11. Dezember 2018
|Barcelona equal Champions League record|
|Composed and controlled Liverpool see off Napoli to progress|
|Tenerife back to winning ways, AEK beat Hapoel|
|Howedes ´hurt´ after emotional Schalke return ends in defeat|
|Kane ´buzzing´ over ´not bad´ draw at Barcelona|
|Robertson hails Alisson´s ´unbelievable´ save as Liverpool progress|
|Red Star Belgrade 1 Paris Saint-Germain 4: Neymar brilliance helps secure Group C top spot|
|Inter 1 PSV 1: Icardi header not enough for the Nerazzurri|
|Liverpool 1 Napoli 0: Superb Salah sends Reds through|
|Club Brugge 0 Atletico Madrid 0: Simeone´s men miss out on top spot|
|Barcelona 1 Tottenham 1: Lucas rescues Spurs late on to secure progress|
|Monaco 0 Borussia Dortmund 2: Guerreiro double snatches top spot from Atletico|
|Butler´s groin strain ´nothing significant´ – 76ers coach Brown|
|Woakes, Curran among leading lights at IPL auction|
|Blue Jays release five-time All-Star Tulowitzki|
|Mourinho: Professionals care more than the fans|
|Casillas reaches 100 Champions League wins|
|Expansion franchise Cincinnati sign Garza, send Kamara to Rapids|
|Manchester City sign United States goalkeeper Steffen for reported £7m|
|Schalke 1 Lokomotiv Moscow 0: Russians miss chance for Europa League reprieve|
|Galatasaray 2 Porto 3: Terim´s men into Europa League after penalty drama|
|Jackman leaves Dragons role|
|Tottenham boosted as Barcelona bench Messi|
|Mane and Henderson in Liverpool XI to face Napoli|
|Mourinho shoots down question over how to get the best from Pogba|
|Ronaldo to start as Allegri aims to avoid Champions League big guns|
|Odriozola: I´m in love with Benzema, he´s the best number nine in the world|
|Vikings fire OC DeFilippo after loss to Seahawks|
|Marcelino suggests Valencia open to Batshuayi departure|
|Bottas to make rally debut in title-winning M-Sport Ford Fiesta|
|Kovac dismisses Pavard speculation|
|Yaya Toure leaves Olympiacos after just five appearances|
|Riise challenges Liverpool to banish Champions League disappointment against Napoli|
|We rallied around it - Durant on Green confrontation aftermath|
|Valencia ´p****d off´ with Fellaini´s controversial Young Boys winner - Soler|
|More must be done to combat racism at Premier League grounds – Chalobah|
|Napoli will not sack ´big signing´ Ancelotti if they miss Champions League qualification, says De La|
|Guardiola not interested in ´exceptional´ Saul|
|Shai gives Windies hope with thrilling ODI run chase|
|Ten Hag unsure whether to risk Ajax stars against Bayern|
|Erasmus to work with Bulls as Springboks assist Super Rugby sides|
|Paul Gascoigne pleads not guilty to sexual assault|
|Joshua is ´begging´ for unification fight, claims Wilder|
|Silva, Fernandinho add to Guardiola´s injury woes|
|Hosszu storms to 14th gold, Seto smashes Le Clos´ world record|
|Raheem is an incredible human being - Guardiola rallies behind City star Sterling|
|Sexton pens IRFU extension until 2021|
|Ajax boss Ten Hag can do big things, says Bayern chief Rummenigge|
|He´s good at basketball – Kerr running out of superlatives for Curry|
|Green thrilled to make Warriors return in victory over Timberwolves|
|Madrid squad great and humble - Solari responds to Ronaldo|
|Langer unsure what to expect from Perth wicket|
|Fournette subjected to alleged racial abuse in Titans loss - Marrone|
|Better and better - Mbappe hails Neymar link|
|It´s the end of one of the best movies you could ever see - James pays tribute to retiring Wade|
|NASA invites Curry to see moon rocks|
|No plan B for LaLiga Miami game after Barcelona withdrawal|
|Messi´s English haul, Neymar eyes hat-trick record - Champions League in Opta numbers|