Newcastle fought back to beat Bordeaux-Begles on the road while Edinburgh entered the record books in the second round of fixtures in this season's European Challenge Cup.
The Falcons trailed 17-7 at the break but rallied in the second half, grabbing a rare win on French soil thanks mainly to Toby Flood's 11-point haul.
The fly-half scored a try and kicked three conversions to secure a 21-20 triumph that puts Newcastle ahead of their opponents.
The Dragons meanwhile defeated Enisei-STM 28-21 in Moscow to sit third in Pool 1.
A big 'merci' to @UBBrugby for a simply incredible game. Can't wait to do it again at Kingston Park later in the season!— Newcastle Falcons (@FalconsRugby) October 21, 2017
Pau are the new leaders in Pool 3 after recovering from 30-7 down at half-time to defeat Zebre 38-33 in a thriller at the Stadio Lanfranchi, where the hosts had Eduardo Bello sent to the sin bin in the second half.
In Pool 4, Edinburgh secured a second successive bonus-point victory as Richard Cockerill's side ran in 10 tries in a 73-14 hammering of Krasny Yar in Moscow.
Full-back Blair Kinghorn and replacement prop Murray McCallum both crossed twice as Edinburgh posted the biggest win in the club's history.
In the same group, Stade Francais are still searching for their first win of the competition after going down 44-7 to London Irish.
Topsy Ojo marked his record-breaking 281st appearance for the Exiles with two tries as the Aviva Premiership strugglers recorded just their second win of the campaign.
The battle of the two unbeaten teams in Pool 5 saw Connacht run out 15-8 victors over Worcester, although Jono Lance's 74th-minute penalty secured a losing bonus point for the beaten Warriors.
21. November 2017
|Conte unhappy with Chelsea´s fixture congestion|
|Pepe tells Ronaldo: Come to Besiktas!|
|Clement expects Abraham to shake off back injury for Bournemouth clash|
|Oddo replaces sacked Del Neri at Udinese|
|F1 Raceweek: Contract talks for Hamilton, Alonso at Le Mans and Kvyat´s snub|
|Bartomeu hints at January Barcelona signings|
|Davis Love III to have hip-replacement surgery|
|Massa eyes final flourish in Abu Dhabi|
|Bears TE Zach Miller out of hospital three weeks after serious injury|
|Emery defends ´responsible´ Neymar from lifestyle criticism|
|Wales lose Williams and Cuthbert for All Blacks clash|
|Australia enlist Bolt to sharpen up Ashes preparations|
|Wimbledon will not be the same without her – Duchess pays tribute to Novotna|
|Del Neri sacked by Udinese|
|Everton striker Niasse facing two-match ban after FA diving charge|
|Wyatt makes history as England salvage Women´s Ashes draw|
|Lampard excited by English clubs in Champions League|
|Kvitova ready for ´second career´ to start in 2018|
|Williams deny Kubica deal has been agreed|
|Thiago and Coman back for Bayern´s trip to Anderlecht|
|Prior launches second Lyon attack|
|Dybala hails Messi as ´our Maradona´, wants to play with Neymar|
|Stokes has let England down - Warner wades in ahead of Ashes opener|
|Sherwood talks up Spurs as potential Champions League winners|
|Borussia Dortmund on the brink as Real Madrid eye progress - Champions League in Opta numbers|
|Hughton hopeful on video assistance after Brighton denied penalty|
|Klopp staying calm over Salah form|
|Irving leads Celtics to 16th straight win|
|He Said What?! The Best NFL quotes of week 11|
|They don´t have magic balls – Cook plays down Australia pace attack|
|Falcons hold off Seahawks|
|Griezmann: I don´t regret staying at Atletico|
|Rogers tells Paine to enjoy Ashes: It´s just a game!|
|Warner ready for first Ashes Test despite neck injury|
|Ashes newcomer Bancroft thought Test chance was gone - Voges|
|Warner suffers injury scare ahead of Ashes|
|Guardiola dismisses Champions League favourites tag|
|Jackson excited about Gordon´s return: I get to open a new toy|
|Nuggets head coach Malone suspended for one game|
|Steelers OT Gilbert handed four-game PED suspension|
|Prior hits back at ´ridiculous´ claims as Lyon hopes Australia end careers|
20. November 2017
|Dolphins QB Cutler placed in concussion protocol|
|Navratilova leads tributes to ´amazing´ Novotna after her death at 49|
|Brighton and Hove Albion 2 Stoke City 2: Gross, Izquierdo extend home unbeaten run|
|Dimitrov braced for Australian Open expectations|
|Broncos fire offensive coordinator Mike McCoy|
|England won´t suffer Gabba ambush, Malan claims|
|Rose in contention to face Dortmund as Pochettino denies ´issue´ with defender|
|Benzema knows he can give more – Zidane|
|I´ve fulfilled my dreams already – Klopp has no plans to coach Barcelona|
|Memorable Ashes Moments: Unlikely saviour Agar falls agonisingly short|
|Wallabies coach Cheika faces investigation|
|The Ashes: Australia squad profiles|
|Aubameyang will face Tottenham, Bosz confirms|
|Klopp expects Matip to face Chelsea, Lallana return getting ´nearer´|
|Brown could return for England, Underhill out|
|Haye´s rematch with Bellew off due to bicep tear|
|The Ashes: England squad profiles|
|Gatland vows not to rise to New Zealand media barbs|
|Berizzo looking to former Red Aspas to provide lessons for Sevilla|
|Mangala ready to pounce, but realistic on Man City playing time|
|The Ashes: How the urn will be won - the case for Australia and England|
|Innovation key as WTA Media embraces evolving viewing habits|
|Trump calls for Lynch to be suspended as anthem row returns|
|Mendy injury means Aguero or Jesus for Guardiola|
|Kohli proud of India after almost snatching Kolkata win|
|The Ashes: Key contests in the battle for the urn|
|Guardiola sends ´big hug´ to ´amazing, so gentle´ Pulis|
|Tavecchio quits as head of FIGC, claims board have refused to resign|
|Benedetto facing Argentina World Cup KO with cruciate injury|