Mesut Ozil and Aaron Ramsey will be rested for Arsenal's home Europa League opener against Cologne.
Manager Arsene Wenger confirmed the midfield duo have been afforded a rest for Thursday's match at the Emirates Stadium after their international endeavours with Germany and Wales respectively.
Wenger did not confirm any of his other planned changes, although Petr Cech, Laurent Koscielny, Alexandre Lacazette, Danny Welbeck and Granit Xhaka all missed training on Wednesday along with Ozil and Ramsey, perhaps with Sunday's crucial away Premier League game against Chelsea in mind.
Francis Coquelin, meanwhile, is out for three weeks after sustaining a hamstring injury in the victory over Bournemouth last time out.
"Overall the injury situation is not too bad," Wenger said.
"On the injury front we have no big problems, a few players have some response to the fact they played two international games like Ozil and Ramsey, who are rested completely.
"Coquelin is out for three weeks. I don't give the team out today, I will give it out on Thursday."
Wenger was asked for an update on midfielder Jack Wilshere, who could make his first Arsenal appearance in over a year against Cologne.
"Every game is an opportunity for him," said Wenger. "This season is a good opportunity for him as well.
"I believe that first of all [he has] to continue to work with the spirit he works and focus.
"I believe as well there was always a huge pressure on him to come back as quickly as possible and to expect a lot. If he can keep calm and focus on his job then he is on a good way.
"For me, in training, he is getting stronger every day. That is what we want from him. He has been injured at the start of the season from last season so he was a bit behind the other players but now he is getting better and better."
Olivier Giroud appeared in front of the media alongside Wenger and is expected to play, while Alexis Sanchez and Hector Bellerin trained with the squad as part of the club's pre-match preparations.
18. Juni 2018
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|Team effort needed for Japan to stop James, says Nishino|
|BREAKING NEWS: Di Francesco extends Roma contract|
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|Hamilton hopes to avoid ´boring´ French Grand Prix|
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|Cisse hails Mane as ´one of the best players in the world´|
|Forsberg falls flat as Granqvist proves Sweden´s hero|
|Sweden 1 South Korea 0: Granqvist´s VAR-assisted penalty settles tight game|
|Nishino concerned Japan players affected by Osaka earthquake|
|Isco pleased with Lopetegui´s Real Madrid appointment|
|Hazard hints at Real Madrid interest|
|Wasps disappointed as Wilson joins Scotland backroom staff|
|Hierro has full confidence in De Gea|
|Russia will stop Salah - Cherchesov|
|Allen signs new four-year Stoke contract|
|England issue update over injured duo Stokes and Woakes|
|Mancini leaves door open for Buffon´s Italy return|
|Alli calls for England to be ruthless in World Cup opener|
|Tahir rested as Proteas call up uncapped duo|
|Uruguay v Saudi Arabia: Centurion Suarez seeks World Cup redemption|
|Portugal v Morocco: Hat-trick hero Ronaldo hunts stricken Atlas Lions|
|Argentina didn´t draw because of Messi´s missed penalty - Maradona|
|Wenger heaps praise on France star Kante|
|If VAR helps referees, I´m not against that – Australia´s Sainsbury|
|Kimmich questions Germany mentality after shock defeat|
|Roberts to leave Warrington Wolves|
|Australia talent Arzani ready to make the jump from A-League|
|Lewandowski: I can be at the top until I´m 35|
|All Blacks winger Savea confirms Toulon switch|
|Free Fall available for France after red card rescinded|
|South Korea can progress from wide-open group, says Park Ji-sung|
|Gordon called up by Wallabies to replace injured Genia|
|Germany can still win World Cup, insists Werner|
|Man United & Real Madrid talk not affecting Milinkovic-Savic|
|Out-of-contract Ruiz focused on Costa Rica|
|Southgate will not bombard England with last-minute instructions|
|Muller: Germany under extreme pressure|
|Rangers score four runs in ninth to pick up walk-off win over Rockies|
|U.S. Open champion Koepka happy to continue being ´overlooked´|
|Pogba: I´m the most criticised player in the world|
|Maradona: Sampaoli´s game plan against Iceland was a disgrace|
|De Gea will bounce back from error – Marchena|
|Slater named for Maroons return|
|Woods, Faldo, Harrington and Koepka – U.S. Open champion joins fine club after successful defence|
|Fleetwood positive despite falling short at U.S. Open|
|Jesus: I had no reason to play for a penalty|
|Hernandez admits to exaggerating fouls against Australia|
|Koepka says winning two U.S. Opens not even in his ´wildest dreams´|
|Hernandez: Griezmann an idol at Atletico|
|Sri Lanka take charge despite Gabriel exploits|
|U.S. Open final-round timeline: How clinical Koepka kept his crown|
|Koepka fights off challengers to successfully defend U.S. Open title|
|´Aching´ Neymar urges referees to intervene|
|BREAKING NEWS: Koepka holds on to defend U.S. Open title|
17. Juni 2018
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|Djokovic: Mental battle will be Murray´s biggest|
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|Brazil the latest favourites to stumble, but Tite and Neymar won´t panic|
|Magnificent Fleetwood matches U.S. Open record with closing 63|
|Brazil 1 Switzerland 1: Zuber pegs back below-par Selecao|
|Warrington hold off Wakefield fightback, Tigers held despite Hitchcox heroics|
|Germany follow trend of poor starts for World Cup champions|
|Reed on the charge as U.S. Open race hots up|
|Milinkovic-Savic can play for any team in Europe, says Crespo|
|Southgate keen to unleash his bold new England|
|Konta fumes as Barty takes Nottingham title|
|Kante hails Pogba´s match-winning contribution|